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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T83121 |
Anatumomab mafenatox
ABR-214936 |
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Anatumomab mafenatox (ABR-214936)是一种73 KDa的重组蛋白,针对广泛表达于恶性肿瘤中的肿瘤相关抗原5T4。该分子构建于修饰后的SEA和小鼠Fab片段之间。Anatumomab mafenatox的主要副作用包括发烧、低血压、疼痛、恶心和嗜睡。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00269 |
5T4/TPBG Protein, Human, Recombinant (mFc)
TPBG,5T4 Protein,M6P1 Protein, |
Human | HEK293 Cells |
5T4/TPBG Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 80-110 KDa and the accession number is Q13641. | |||
TMPY-05033 |
5T4/TPBG Protein, Human, Recombinant (aa 60-345, His)
5T4AG,trophoblast glycoprotein,WAIF1,M6P1,... |
Human | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 60-345, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.1 kDa and the accession number is Q13641. | |||
TMPY-06214 |
5T4/TPBG Protein, Mouse, Recombinant (hFc)
trophoblast glycoprotein,AW495680,5T4,WAIF... |
Mouse | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 62.5 kDa and the accession number is Q9Z0L0. | |||
TMPY-06191 |
5T4/TPBG Protein, Mouse, Recombinant (His)
trophoblast glycoprotein,WAIF1,5T4,AW49568... |
Mouse | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.2 kDa and the accession number is Q9Z0L0. | |||
TMPH-02437 |
5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc)
TPBG,WAIF1,Wnt-activated inhibitory factor 1,Trophoblast gly... |
Cynomolgus | HEK293 Cells |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 39.9 kDa and the accession number is Q4R8Y9. | |||
TMPJ-01153 |
5T4/TPBG Protein, Cynomolgus, Recombinant (His)
TPBG,5T4,M6P1,WAIF1,5T4AG |
Cynomolgus | HEK293 Cells |
5T4/TPBG Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-80 KDa and the accession number is Q4R8Y9. | |||
TMPH-03392 |
5T4/TPBG Protein, Rat, Recombinant (His & SUMO)
Wnt-activated inhibitory factor 1,Trophoblast glycoprote... |
Rat | E. coli |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 51.8 kDa and the accession number is Q5PQV5. | |||
TMPK-00271 |
TPBG/5T4 Protein, Human, Recombinant (His & Avi)
M6P1,WAIF1,5T4,TPBG,5T4AG |
Human | HEK293 Cells |
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs. TPBG/5T4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is Q13641-1... | |||
TMPJ-00268 |
5T4/TPBG Protein, Human, Recombinant (Avi & His), Biotinylated
5T4,M6P1,WAIF1,5T4AG,TPBG |
Human | HEK293 Cells |
5T4/TPBG Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 60-90 KDa and the accession number is Q13641. | |||
TMPK-00270 |
TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled
WAIF1,TPBG,5T4AG,5T4,M6P1 |
Human | HEK293 Cells |
The oncofetal tumor-associated antigen 5T4 (TBGP) has been linked with CSC properties in several different malignancies. 5T4 has functional attributes that are relevant to the spread of tumors including through EMT, CXCR4/CXCL12, Wnt, and Hippo pathways which may all contribute through the mobilization of CSCs. TPBG/5T4 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 38.2 kDa and the accession numb... | |||
TMPY-06317 |
5T4/TPBG Protein, Human, Recombinant (aa 1-355, His)
trophoblast glycoprotein,WAIF1,5T4AG,M6P1,... |
Human | HEK293 Cells |
Trophoblast glycoprotein (TPBG), also known as 5T4, is the therapeutic target of several anticancer agents currently in clinical development, largely due to its high expression in tumors and low expression in normal adult tissues. 5T4/TPBG Protein, Human, Recombinant (aa 1-355, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.15 kDa and the accession number is NP_006661.1. | |||
TMPH-02436 |
5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc)
TPBG,Trophoblast glycoprotein,Wnt-activated inhibit... |
Cynomolgus | E. coli |
May function as an inhibitor of Wnt/beta-catenin signaling by indirectly interacting with LRP6 and blocking Wnt3a-dependent LRP6 internalization. 5T4/TPBG Protein, Cynomolgus, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.9 kDa and the accession number is Q4R8Y9. |